منابع مشابه
Hemodynamic dependence of myocardial oxygen consumption indexes.
We tested the afterload and contractile state dependency of three indexes of myocardial oxygen consumption (MVO2): total energy requirement (Et), pressure work index (PWI), and pressure-volume area (PVA). MVO2 was measured in seven isolated canine hearts at four or five different end-diastolic volumes at each of three settings of afterload resistance and with the hearts contracting isovolumical...
متن کاملHand Grip Strength and Myocardial Oxygen Consumption Index among Coronary Artery Bypass Grafting Patients
Background: Hand grip strength (HGS) is a reliable indicator of peripheral muscle strength. Although, numerous studies have investigated the strength of hand grip; little attention has been given to coronary artery disease (CAD) patients, exploring the relationship between HGS and myocardial oxygen consumption (MVO2) index. The current study aimed to evaluate the interaction between HGS and MVO...
متن کاملIncreased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice.
Altered cardiac metabolism and function (diabetic cardiomyopathy) has been observed in diabetes. We hypothesize that cardiac efficiency, the ratio of cardiac work (pressure-volume area [PVA]) and myocardial oxygen consumption (MVo(2)), is reduced in diabetic hearts. Experiments used ex vivo working hearts from control db/+, db/db (type 2 diabetes), and db/+ mice given streptozotocin (STZ; type ...
متن کاملMyocardial Oxygen Consumption during Ventricular Contraction and Relaxation.
• As early as 1915 it was known that an increase in systolic pressure is accompanied by a greater myocardial oxygen cost than a proportionate increase in stroke volume. Recent investigators have related myocardial oxygen consumption to the product of the mean systolic pressure and the heart rate, or to the integral of systolic pressure in time. In the isovolumetrically contracting ventricle, my...
متن کاملNitroglycerin reduces myocardial oxygen consumption during exercise despite vascular tolerance.
The long-term benefits of nitroglycerin (NTG) therapy are limited by the development of vascular tolerance and endothelial dysfunction in conductance coronary arteries. We have determined whether nitrate tolerance extends to NTG effects on myocardial O2 consumption (MV(O2)) and the ability of endogenous nitric oxide (NO) to modulate MV(O2) during exercise. In chronically instrumented dogs (n = ...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 1976
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(19)40278-x